Sample Essay on:
Synaptic Transmission

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Essay / Research Paper Abstract

This 5 page paper examines the process of synaptic transmission. The paper starts with the historical view, looking at the way understanding has developed. The processed themselves are then outlined and the paper ends by considering how imbalances can result in clinical conditions. The bibliography cites 4 sources.

Page Count:

5 pages (~225 words per page)

File: TS14_TEsynaptic.rtf

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Unformatted sample text from the term paper:

is essential for the physical and metal health of an individual. To understand this we will first look at the history of the understanding of synaptic transmission, then at how it works and finally at the impact his can have and how chemicals can interfere. The way in which neurons communicate has been the subject of much speculation (Jefferys, 1995). C. Golgi maintained that the brain was made up of syncytium, alternatively S. Ramon y Cajal maintains, after studies which used Golgi stains, that the brains consists of discrete neurons (Jefferys, 1995). After this the discussion shifted to the way in which neurons communicated. The term synapse was first used by C. Sherrington as a description of the neuron contact points (Jefferys, 1995). In the 1930s it was argued that this communication that occurred across the synapses was electrical in nature, whilst others stated they believed it was a chemical reaction (Jefferys, 1995). It was discovered that to some extent both hypotheses were correct although chemical synapses have clear supremacy in the vertebrate brain (Jefferys, 1995). Experiments have gone on to prove that electrical communication that takes place between in three ways (Jefferys, 1995). The first is electronic coupling, this occurs between specific neurons by the use of specific and specialised gap junctions (Jefferys, 1995). These gap junctions are most commonly used by invertebrates, but are also used less frequently in vertebrates (Jefferys, 1995). The second is ephaptic coupling which takes place between closely apposed, but noncontiguous, neuronal membranes (Jefferys, 1995). The third type is classified as field interactions, in this the structures geometry encourages the creation of big extracellular fields which effect the excitability of ...

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