Sample Essay on:
Metabolism; Genetic Basis for Deafness

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Essay / Research Paper Abstract

A 4 page paper containing 2 distinct sections: 1 page on carbohydrates and weight gain, 3 pages discussing the Cx26 gene (GJB2/DFNB1). This gene is associated with autosomal recessive deafness, ranging from moderate to profound. The paper lists and discusses several of the allele variants of this gene. Bibliography lists 6 sources.

Page Count:

4 pages (~225 words per page)

File: CC6_KSbioGeneDiet.rtf

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Unformatted sample text from the term paper:

Metabolic rate varies between individuals and between varying times of the day. Metabolism activities begin slowing in the late afternoon and into the evening. If much of the days intake of high-carbohydrate foods occurs late in the evening, then less of that carbohydrate will be used for immediate metabolic needs. Instead, the body places the nutrients into short-term storage. That short-term energy might be used during the day, but it likely will not be later in the day or at night. Glycolysis "When the body changes from anaerobic to aerobic conditions, glucose consumption decreases dramatically." Aerobic glycolysis is more efficient in generating ATP per mole of glucose oxidized. It is ATP that provides energy to the muscles allowing them to contract. When this occurs under load (i.e., exertion) anaerobic glycolysis produces ATP for red blood cells and muscle tissue. The process is 100 times faster in the anaerobic phase (King, 2004). Exercising when the greatest amount of glucose is available helps to metabolize it away. Part B Gene Selection Cohn, Kelley, Fowler, Gorga, Lefkowitz, Kuehn, Schaefer, Gobar, Hahn, Harris, and Kimberling (1999) described the "phenotype associated with the single most common cause of genetic hearing loss" (p. 546). The authors state that one in 500 children are deaf and that half of the loss is genetic. Of that genetic hearing loss, 80 percent is "nonsyndromic and inherited in an autosomal recessive manner. Approximately 50% of childhood nonsyndromic recessive hearing loss is caused by mutations in the connexin 26 (Cx26) gene (GJB2/DFNB1)" (Cohn, et al., 1999; p. 546), making it the "most common form of autosomal recessive nonsyndromic hearing loss" (Cohn, et al., 1999; p. 546). ...

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