Sample Essay on:
The Biochemistry of Type 1 Diabetes

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Essay / Research Paper Abstract

This 5 page paper focuses on the biochemistry of this disease but also discusses treatment, etiology and symptoms. How insulin therapy works is also included. Bibliography lists 6 sources.

Page Count:

5 pages (~225 words per page)

File: RT13_SA518jd.rtf

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Unformatted sample text from the term paper:

able to produce insulin on their own. Complications arise related to organ function and good control is key to successful management of this condition. For example, insulin resistance and hyperinsulinemia can exacerbate heart disease (Bond & Yates, 2004). While the etiology of diabetes is not known, at least not in the traditional sense, there is some speculation that cows milk could play a role (Barnard, 2003). There seems to be a strong genetic factor but twin studies have revealed that Type 1 occurs in less than 50% in an identical twin of a diabetic (Hussain & Vincent, 2005). Extragenetic conditions may contribute to the disorder (2005). The disease usually presents in childhood, and more often than not in preadolescence (2005). Symptoms include blurred vision, frequent urination and fatigue (2005). Insulin-dependent diabetes mellitus or IDDM or Type 1 diabetes is defined "by the development of ketoacidosis in the absence of insulin therapy" (King, 2005). In other words, the diabetic with this type is dependent on insulin. This type of diabetes is actually the result of an "autoimmune destruction" as it respects pancreatic cells (2005). It is actually an autoimmune reaction to the antigens that are found in the islet cells located in the pancreas (2005). Other endocrine autoimmunities are associated with this type, such as Addison disease and the disease tends to run in families (2005). What happens is that prior to the onset of diabetes, the body is unable to cope with certain immune cells and they in turn attack the beta cells that produce insulin ("Joslin," 2005). The antibodies most prevalent in diabetics with Type 1 diabetes go against islet cell cytoplasmic proteins (ICCA) at a rate of about 90% as compared with people who do not have diabetes; for them, ...

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